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The 5 Teams On “Upset Alert” Week 2

Here are the five teams on “Upset Alert” for Week 2.

Week 2 of the 2017 college football season is here, and we have a bunch of big-time matchups.

What top 25 teams are at risk of being upset Week 2?

Here are the five teams we’re placing on “Upset Alert" this Saturday.

1. No. 3 Clemson vs. No. 13 Auburn, 7 p.m ET on ESPN

I know, I know. Is this really an upset? Sure, Auburn is a 5.5-point underdog but the Tigers are also ranked No. 13 in the country and play in the tough SEC.

Still, we're talking about a Clemson team that is the defending national champions and hasn't lost in Death Valley since October 2013. This would be a massive win and statement for Gus Malzahn's crew, and would immediately legitimize their case as bona fide College Football Playoff contenders.

2. No. 17 Louisville at UNC, 12 p.m. ET on ESPN

The good news for Louisville? Lamar Jackson is still Lamar Jackson, and the reigning Heisman Trophy winner was outstanding in Week 1.

The bad news? The Cardinals struggled a bit with Purdue and gets a UNC team that should be extra motivated after getting knocked off by Cal in its opener. Louisville is nearly a double-digit favorite but they must be careful here.

3. No. 20 Washington State vs. Boise State, 10:30 p.m. ET on ESPN

The Cougars are positioning themselves as a potential Pac-12 sleeper this season, and they have a tough non-conference test here.

Boise State isn't afraid of playing marquee opponents on the road, and the Broncos still possess a quality quarterback in Brett Rypien. If they can slow Wazzu down just enough, they might have what it takes to spring the upset.

4. No. 4 Penn State vs. Pitt, 3:30 p.m. ET on ABC

Let's be honest here: we are expecting Penn State will win this one. The Nittany Lions owe their rivals one after Pitt beat them last season.

However, this is a rivalry game, and those things sometimes get crazy. While PSU has the clear advantage with talent and home field, Pitt will be motivated and could put a scare in them.

5. No. 6 USC vs. No. 14 Stanford, 8:30 p.m. ET on FOX

The Trojans are 6.5-point favorites, but are coming off a lackadaisical opening win over Western Michigan.

Stanford is well-coached and well-equipped to pull one out on the road. USC will need quarterback Sam Darnold to be at his best to avoid defeat.