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Khris Middleton Injury Revealed: NBA World Reacts

Kris Middleton driving to the basket.

MILWAUKEE, WI - APRIL 22: Khris Middleton #22 of the Milwaukee Bucks drives to the hoop during the first half against the Toronto Raptors of Game Four of the Eastern Conference Quarterfinals during the 2017 NBA Playoffs at the BMO Harris Bradley Center on April 22, 2017 in Milwaukee, Wisconsin. (Photo by Mike McGinnis/Getty Images)

The Milwaukee Bucks' quest to win back-to-back NBA championships has taken a significant hit. Khris Middleton will not be available during the team's second-round series against the Boston Celtics, according to NBA insider Shams Charania.

Middleton has been diagnosed with a Grade 2 MCL sprain in his left knee. He's expected to miss the Bucks' entire second-round series. In the event Milwaukee somehow advances, he might even miss the Eastern Conference Finals.

"The left MCL injury of Bucks All-Star Khris Middleton is a Grade 2 sprain and he is expected to miss the entire second-round series vs. Celtics, sources tell @TheAthletic @Stadium," Charania tweeted this morning. "The recovery of Grade 2 MCL places a potential Conference Finals in jeopardy for him as well."

The Bucks are in serious trouble. They'll face the red-hot Celtics this Sunday without their No. 2 option.

Most NBA fans now think the Celtics are going to win the series in five.

"Celtics in 5. Giannis forces the fifth game on brink of elimination, but bucks offense otherwise cannot penetrate Bostons fully healthy defense. With Middleton… Celtics in 7. He’s a difference maker and performs well against Boston every single game. It’s uncanny."

"Obviously anything can happen, but I'd be very surprised at this point if the Celtics didn't beat the Bucks in 5 or 6 without Middleton."

"Sorry I just don’t see a world where bucks even healthy beat the Celtics, let alone without their Robin"

Giannis Antetokounmpo will need a superhuman performance to get the Bucks past the C's without Middleton in the lineup.