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NFL World Reacts To The Rams' Tough Injury News

A Los Angeles Rams helmet during a game vs. the Tampa Bay Buccaneers.

INGLEWOOD, CA - SEPTEMBER 26: Los Angeles Rams helmet during a game between the Tampa Bay Buccaneers and the Los Angeles Rams at SoFi Stadium on September 26, 2021 in Inglewood, California. (Photo by Jordon Kelly/Icon Sportswire via Getty Images)

The Los Angeles Rams added insult to injury after last night's loss to the San Francisco 49ers.

Starting center Coleman Shelton has suffered a high-ankle sprain and will be out for at least the next 4-6 weeks. Safety Jordan Fuller will miss the next 2-4 weeks with a hamstring issue, head coach Sean McVay told reporters on Tuesday.

The NFL world took to Twitter to react to this unfortunate injury news for the reigning Super Bowl champs.

"This O-line has been shuffled a ridiculous amount only 4 weeks into the season," one fan wrote.

"Dang… especially with a quick turn around vs the Cowboys," another said.

"Rams had elite injury luck until they won a title. Gotta be thankful about that I guess," another added.

The Rams were already dealing with some significant offensive line injuries. During last night's 24-9 loss to the 49ers, quarterback Matthew Stafford had very little time to get the ball off — taking a whopping seven sacks against the San Francisco pass rush.

The Rams are now 2-2 to start the 2022 season. They'll look to bounce back in a Week 5 matchup against the Dallas Cowboys on Sunday.