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A No. 1 Seed Is Only Leading By 4 Points With 12 Minutes To Go

A closeup of Bill Self in a Kansas Jayhawks uniform.

SAN ANTONIO, TX - MARCH 30: head coach Bill Self of the Kansas Jayhawks looks on during practice before the 2018 Men's NCAA Final Four at the Alamodome on March 30, 2018 in San Antonio, Texas. (Photo by Tom Pennington/Getty Images)

We've got a serious "Upset Alert" taking place at the 2018 NCAA Tournament right now.

A No. 1 seed has never lost an NCAA Tournament game. Is that going to change this afternoon?

Kansas, the No. 1 seed in the Midwest Region, is in an extremely tight game with No. 16 seed Penn.

The Quakers are trailing the Jayhawks by just 4 points with a little less than 12 minutes to play. Watch out, KU!

ESPN's Pablo Torre picked Penn to upset Kansas on Around The Horn. It's safe to say he's pretty excited.

The game is being televised on TBS. You're going to want to get to a TV ASAP.

ESPN currently lists Kansas' winning percentage at about 85 percent. Is that too high?

We're going to find out in the coming minutes. It appears the game is going to be a tight one until the clock hits 0:00.

The winner moves on to face the winner of VT-Alabama.