Now that every Week 1 matchup is officially known, sportsbooks have released their initial point spreads. There are already two overwhelming favorites for the first weekend, albeit so much can change between May and September.
No one knows yet if the 49ers will start Jimmy Garoppolo or Trey Lance, but apparently that doesn’t matter. As long as Nick Bosa, Georgie Kittle and the rest of Kyle Shanahan’s squad is healthy for the season opener, they are expected to take care of business against an inexperienced Lions team.
The second-biggest favorite heading into Week 1 of the NFL season just so happens to come out of the NFC West as well. The Los Angeles Rams are currently favored by 7 points for their season opener against the Chicago Bears.
Chicago added an exciting quarterback prospect to its roster in Justin Fields, but there’s no telling if he’ll win the starting job over Andy Dalton.
It's only May but it still feels great to say this:
NFL Week 1 odds are out 🏈 pic.twitter.com/kLuVrXjxG5
— BetMGM 🦁 (@BetMGM) May 12, 2021
The Buffalo Bills, Kansas City Chiefs and Tampa Bay Buccaneers are also considered heavy favorites heading into their season openers.
On the flip side, the Denver Broncos, Los Angeles Chargers and New Orleans Saints are barely favored over their Week 1 opponents.
Which matchup are you circling on your calendar for Week 1 of the 2021 season?