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Chargers Make Decision On Derwin James Before Kickoff

Derwin James of the Los Angeles Chargers reacts to broken pass.

CARSON, CA - DECEMBER 22: Derwin James #33 of the Los Angeles Chargers reacts to a broken pass play during the second half of a game against the Baltimore Ravens at StubHub Center on December 22, 2018 in Carson, California. (Photo by Sean M. Haffey/Getty Images)

The Los Angeles Chargers will be without the heartbeat of their defense on Sunday. Per ESPN's Adam Schefter, All-Pro defensive back Derwin James is sidelined for this week's game.

"Chargers’ S Derwin James inactive today vs. the Giants," Schefter tweeted. James was questionable heading into the game with a hamstring injury. After two injury-plagued seasons, the star safety has played in all 12 games for the Chargers this year. Playing in 98-percent of the team's defensive snaps. The former Florida State standout leads LA in tackles with 100. He's also added three forced fumbles, two picks, and a pair of sacks. Despite the New York Giants' offensive struggles, James' absence will still be a significant one.

Luckily, the team won't be without Pro Bowl corner Chris Harris Jr. as well. Harris was listed on the team's Reserve/COVID-19 list earlier in the week. However, it looks like he and receiver Mike Williams will be back on the field against the G-Men.

Star receiver Keenan Allen remains out.

The Chargers and Giants kick off in the middle window of Sunday's action on FOX.